Preliminary inspection by the Care Quality Commission rated the hospital as requiring improvement.

[2] Planning for Arrowe Park Hospital began in the 1960s, although building did not start until the late 1970s.

[4] In March 2011, following remodelling work at a cost of £11.5 million, the maternity and gynaecology unit was renamed Wirral Women and Children's Hospital.

[5][6] In January 2020, the hospital was designated the quarantine site for British nationals evacuated from China at the start the COVID-19 pandemic.

[9] In November 2024, the trust announced a major incident at the hospital "for cyber security reasons", resulting in the cancellation of outpatient appointments.