[1] Hambardzumyan was a teacher at College after Aram Manukyan in Shushi from September to Novovember 1993, later worked as assistant at YSU Faculty of History (October–December 1995).

From 1999 to 2005, he was a chief specialist of the NA Armenian Revolutionary Federation faction.

[1] In 2005-2008, he worked as Social Protection Sphere Loan Project Coordinator.

In June 2008, Arsen Hambardzumyan was appointed RA Minister of Labor and Social Affairs.

He is the author of two research works[clarification needed] and about 30 newspaper articles.