His formidable efforts at translating and compiling major doctrinal and polemical work from Greek gave a novel impetus to the Georgian patristic and philosophical literature.
According to historic tradition Arsen was born in Iqalto in the province of Kakheti, east of Tbilisi, Georgia's modern capital.
He was educated in Constantinople at the Mangana academy, the centre of Byzantine philosophical activity and classical learning, and served as a monk on the Black Mountain near Antioch under the tutelage of Ephraim the Minor.
[1] Iqaltoeli probably played a key role in the debate between Armenian and Georgian churchmen organized by David IV in a futile attempt to reconcile doctrinal differences between the two churches in 1123.
The most complete surviving manuscript of this work (S-1463) dates to the 12th-13th century and includes sixteen key authors, such as Anastasius Sinaita, John of Damascus, Theodore Abucara, Michael Psellos, Cyril of Alexandria, Nikitas Stithatos, Pope Leo the Great and others.