The main plot takes place in late antiquity Greece which is under the apparent influence of Rome, as well as during the first years of Christianity, in the 4th century AD, and follows the struggle of sick athlete Igesias to get well – by putting his hopes on Asclepius and his sanctuary in Epidaurus.
The scenery (the Asklepieion of Epidaurus and the cults relating to the treatment of illnesses and human health at a time when new -Christian- ideas are emerging) clearly reflects the intention of Sikelianos to talk about a time of conflict between two major traditions (the Greek and the Christian spirit) and their final reconciliation and synthesis –in the work.
The character of Igesias (leadership) (a symbol -with a proper name for the political events occurring during the last editing of the work; both as a concept for the people and also the poet) is carrying within the purity of the ancient ideals, but also embraces the Christian beliefs, proceeding to a blending of the two worldviews.
At the same time, the soul of the poet Igesias - is cured from all personal passions and problems and he finds Health (healing as a principle is apparent throughout text that has been salvaged to date), a meeting that is affecting the situation (and the desire for treatment) of the poet in the final period of writing of the play: Sikelianos is ill and is gradually unable to leave his sickbed (the end is not far away).
It has been suggested that Igesias – who comes from Argos – be identified with the "sick" Orestis of the ancient drama, who also comes from Argos (many schemes and elements of the tragedy of Sikelianos, especially those relevant to Igesias, - the illness that he has which is a result of a mental illness - the therapy through sleep and dreams that are directly suggestive of what we would in ancient drama call "correspondences" and "ideals").