Close to the border with the county of Hertfordshire, it is in the hamlet of Odsey, slightly north of the Icknield Way, a Roman Road that is now the A505.

The station then passed on to the Eastern Region of British Railways on nationalisation in 1948.

When Sectorisation was introduced in the 1980s, the station was served by Network SouthEast until the Privatisation of British Railways.

Off-peak, all services at Ashwell & Morden are operated by Thameslink using Class 700 EMUs.

The typical off-peak service in trains per hour is:[3] During the peak hours, the station is served by a number of additional stopping services between Cambridge and London King's Cross, operated by Great Northern.