It has been an important research organism for studying eukaryotic cell biology[1] for over 50 years,[2] being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, tubulin, chromatin, nucleokinesis, pathogenesis, metabolism,[3] and experimental evolution.

A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner.

[5] A sequence with 13-fold coverage was publicly released in March 2003;[5] analysis of the annotated genome was published in Nature in December 2005.

Recently, several caspase-like proteases were isolated from A. nidulans samples under which programmed cell death had been induced.

Anidulafungin[8] is a semisynthetic lipopeptide antifungal drug of echinocandin B subclass, derived from a fermentation product of A. nidulans var.