It is located in the north-eastern part of the municipality, with the Marlach river flowing through it.

From 1798 to 1814, when the Palatinate was part of the French Republic (which became the Napoleonic Empire in 1804), Assenheim was in the Canton of Mutterstadt [de].

After the Congress of Vienna in 1815, Assenheim initially belonged to the Austrian Empire and then moved to the Kingdom of Bavaria in 1816.

After the Second World War, Assenheim was part of the then newly formed state of Rhineland-Palatinate within the French occupation zone.

On June 7, 1969, during the course of the first regional reorganization in Rhineland-Palatinate [de] Assenheim was merged with the neighboring municipality of Hochdorf to form Hochdorf-Assenheim.