The Cathedral of Saint Mary (Spanish: Catedral de Santa María) is a Roman Catholic church in Astorga, Spain.

The construction lasted until the 18th century, thus to its original Gothic style appearance were added elements from later styles, such as the Neo-Classicist cloister (18th century), the Baroque towers, capitals and the façade, and the Renaissance portico.

With a rectangular layout, with apsidal chapels, very clear and bright, it has an architectural closeness to German Gothic.

The interior houses numerous artworks, such as the Flemish-Spanish retablo of St. Michael, and the large high altar by Gaspar Becerra (1558), considered a masterwork of the Spanish Renaissance sculpture.

Next to the church is the Neo-medieval Episcopal Palace, designed by Antoni Gaudí.