Astroblepus homodon is a species of catfish of the family Astroblepidae.

It can be found in Colombia.

[3][4] Astroblepus homodon is endemic to Colombia, where it is found in the Magdalena-Cauca rivers and Pacific slope river basins, occurring at altitudes between 480 and 2,000 metres (1,570 and 6,560 ft) in clear, fast flowing streams.

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