At Risk is a 1988 book by Alice Hoffman about Amanda, an 11-year-old girl who contracts HIV from a blood transfusion.

Amanda lives with a typical suburban family in the town of Morrow, Massachusetts until she comes down with a fever and a blood test for HIV returns as positive.

As the news spreads, other parents, fearful of their own children catching the disease, cut off contact with the family.

Her principal decides to counter this by giving the whole school a class-by-class sex education talk.

While Amanda's death is portrayed to be inevitable, the novel concludes with an open ending - the special friendship between Charlie and Sevrin.