The Men's 100 metres T12 event for the 2012 Summer Paralympics took place at the London Olympic Stadium on 3 and 4 September.

[1] The T12 category is for athletes with visual impairment.

Athletes in this category will generally have some residual sight, the ability to recognise the shape of a hand at a distance of 2 metres and the ability to perceive clearly will be no more than 2/60.

Prior to the competition, the existing World and Paralympic records were as follows.

rule: winner of each heat (Q) plus best second place (q) qualified.