The Atlantic and Danville Railway (reporting mark AD) was a Class I railroad which operated in Virginia and North Carolina.

[1] The Southern Railway discontinued service on this branch in 1932; the Gray Lumber Company continued to use it for logging operations until 1938.

The railroad employed 315 people in 1896, including the company officers, clerks, firemen, engine men, conductors, ticket agents, carpenters, foremen, laborers and telegraph operators and dispatchers.

Outbound freight consisted coal, lumber, and farm products such as flour, wheat, hay, tobacco and fruits and vegetables as well as livestock, meats, wool and leather.

Inbound freight included petroleum, oil, naval stores, cast iron products, machinery, cement, brick, lime, agricultural tools, wagons, alcoholic beverages, furniture and housewares.