She is known for her prolific voice work including Arlene in the Garfield franchise, Stealth Elf in the Skylanders video games, and roles in My Life as a Teenage Robot, Psychonauts 2, Breadwinners, Fallout 3, and Infinity Train.

She has also appeared in a supporting role in several live-action projects, including Mad Men, Big Love, Mosquito State, Fancy Dance, and Everything Everywhere All At Once.

Once again voicing the love interest to a Frank Welker character, she is Ortensia, Oswald the Lucky Rabbit's cat wife in Epic Mickey 2: The Power of Two.

In the 2010 film Red, Wasilewski appeared in a cameo alongside Bruce Willis and John Malkovich in which she played a doomed "gun for hire" sent to assassinate them.

She has made over 100 guest appearances in TV series, such as, 9-1-1, Homecoming, Defending Jacob, Love, Victor, Young Sheldon, Ghosted, Friends, Two and a Half Men, Ally McBeal, George & Leo, Total Security, Saved by the Bell, Party of Five, Diagnosis Murder, State of Grace, The Nightmare Room, Providence, Charmed, Cold Case, ER, General Hospital, Push, The West Wing, Wonderfalls, The Bernie Mac Show, Boston Legal, Scandal, Family Guy, Monk, Mad, The Inside, Without a Trace, and many more.