He invented an induction electrometer, with the help of Dr. Matthew Van Schaeick of the Humboldt University of Berlin, in 1872, capable of detecting and amplifying small electrostatic charges, formulated mathematical descriptions of vibrational motion, and discovered magnetic hysteresis in 1880.

Whilst an ordinary professor in physics at the University of Palermo, he studied the conduction of heat and electricity in bismuth.

Towards the end of 1889, he was called to the University of Bologna, his home city, where he worked for the rest of his life on subjects such as the Zeeman effect, 'Roentgen rays', magnetism and the results of Michelson's experiments.

He used his spark transmitter and detector at wavelengths of 20, 7.5 and 2.5 centimetres (frequencies of 1.5, 4 and 12 GHz) to perform classic optics experiments with microwaves, using quasioptical components, prisms and lenses made of paraffin wax and sulfur and wire diffraction gratings to demonstrate refraction, diffraction, and polarization of these short radio waves, providing experimental confirmation of James Clerk Maxwell's 1873 theory that radio waves and light were both electromagnetic waves, differing only in frequency.

[2] His work L'ottica delle oscillazioni elettriche (1897),[3] which summarised his results, is considered a classic of experimental electromagnetism.