The series was written by Christos Gage, with artwork by Mike McKone and tells the story of a group of young super-powered persons who were selected to join a training academy for the super-hero team, the Avengers.

Marvel announced the launch of Avengers Academy by the creative team of Christos Gage and Mike McKone in March 2010 by releasing a set of teaser images featuring students from the title.

[6] In June 2010, Marvel announced the series will cross over with Thunderbolts #147, which is bookended in the "Scared Straight" storyline featured in Avengers Academy #3 and 4.

[9] In May 2011, Marvel published Avengers Academy Giant Size #1, an 80-page one-shot by writer Paul Tobin and artist David Baldeon.

[11] The subsequent four issues tied into that crossover's epilogue storyline, "Shattered Heroes", during which the series' setting was relocated to the West Coast of the United States, and introduced new part-time and full-time students beginning in Avengers Academy #21 in November 2011,[12] The part-time students include Spider-Girl, She-Hulk (Lyra), Power Man, Machine Teen, Batwing, Butterball, Wiz Kid, Juston Seyfert and his Sentinel, Thunderstrike, Rocket Racer and members of the Loners.

[16] After finding out the truth, Finesse blackmails Quicksilver to teach her everything he was taught in the Brotherhood of Mutants threatening to expose the fact that he stole the Terrigen Crystals and not the Skrull imposter that he claimed to have committed the crime.

They then set up a meeting with Jessica Jones, who had similar issues and Reptil finally opens about many of the things that have been troubling him, but keeps his concerns about his fellow students and the academy private.

[23] Quicksilver helps Finesse seeks out Taskmaster believing him to be her biological father but is called back early to attend a faculty meeting to determine if Tigra's decision to expel Hazmat, Veil, and Striker was just.

[24] After the expelled students are readmitted, Speedball takes them all on a field trip to Stamford, Connecticut, to visit the memorial of the incident that started the Civil War.

When Hardball accuses Reptil of hitting on "his girl", a fight breaks out but is soon broken up by Henry Pym and Speedball.

[28] While the adult Avengers are dealing with the eruption of Mount Etna, Tigra and the students learn that Electro has broken into a French lab.

Back at the academy, Henry Pym then tells the students that he has failed to prepare them for such a fight and they will train harder as a result.

[30] During the 2011 "Fear Itself" storyline, Henry Pym, Quicksilver, Jocasta, and Justice head out to round up criminals who escaped from the Raft.

[38] The Academy takes in Hybrid after being rescued from a firefight with the Purifiers but it is soon discovered that his intended goal is to establish himself as Wraithworld's king.

[40] However Reptil has a change of heart and sends a distress signal to Veil, who returns with Jocasta, and together manage to banish Hybrid from this dimension.

[41] Jocasta reveals that she faked her death because she believes that the Academy is putting the students' lives at risk and has since joined up with Jeremy Briggs and Veil.

After they teleport to a prehistoric dimension and find Old Lace, Nico Minoru reveals that Pym intends to send the youngest Runaways to child protective services.

After talking to Finesse, she witnesses the young mutants from Utopia (now joined by Ricochet, Wiz Kid and Hollow) confronting the Academy students.

[46] Before a battle begins, X-23 and Finesse warn their friends that Shaw's body language indicates that he doesn't mean to hurt anyone, but to help the mutant children to escape.

After both sides agree that the mutant children shouldn't be confined against their will, Tigra suggests to fake a fight in order to justify their escape in front of the cameras at the Academy.

[48] As the Academy staff and students fight Emma Frost, both sides of the battle discuss the ethics in her attempt to destroy Juston's Sentinel.

After Mettle and Hazmat take the cure, Jeremy reveals his true intentions: to depower superhuman beings and re-disperse their abilities to individuals, whom he deems worthy.

After defeating the depowered students with the help of the Young Masters, Briggs extends his offer to Hazmat, Mettle, Striker, and Veil, who accept.

[52] Lightspeed takes off after the missiles and disarms a couple as Veil tricks Briggs' scientists into releasing Jocasta so that she can redirect the rest.

[55] Finesse, Hazmat, Reptil, Striker, Veil, Butterball, and White Tiger all appear as unlockable playable characters in Lego Marvel's Avengers.