She was the first member of the Imperial Family to be born in the Heisei period, the era of her first cousin once removed, Emperor Akihito.

While she was a student at Gakushūin Women's High School, in 2007, she visited New Zealand under a school-sponsored homestay program.

[2] The Princess made short term visits to Camosun College in Victoria, British Columbia, Canada, as part of exchange tours with Josai International University in 2010 and 2011.

On 16 March, Princess Ayako of Takamado graduated from Josai International University and received a master's degree of social welfare.

[3] Princess Ayako became formally engaged in a ceremony on 12 August 2018 to businessman Kei Moriya, a Keio University graduate who works for the shipping firm Nippon Yusen.

[8] The bride wore "a kimono robe and hakama pants", while the groom appeared in a morning suit and was given a top hat that had previously belonged to Ayako's father, Prince Takamado.