Masako, Princess Takeda (恒久王妃昌子内親王, Tsunehisa Ōhi Masako naishinnō), born Masako, Princess Tsune (常宮昌子内親王, Tsune-no-miya Masako Naishinnō, 30 September 1888 – 8 March 1940), was the tenth child and sixth daughter of Emperor Meiji of Japan, and the third child and second daughter of Sono Sachiko, the Emperor's fifth concubine.

Masako was born in Tokyo Prefecture, the daughter of Emperor Meiji and Lady Sachiko.

Her future husband, Prince Tsunehisa Takeda, was the eldest son of Prince Kitashirakawa Yoshihisa and thus the brother of Prince Kitashirakawa Naruhisa.

Emperor Meiji authorized Prince Tsunehisa to start a new princely house in March 1906, largely to provide a household with suitable status for his sixth daughter Princess Tsune.

Prince Takeda married Princess Masako on 30 April 1908, by whom he had a son and a daughter: She died on 8 March 1940, aged 51.