[1] Azimzade received no artistic education and was self-educated;[1][2][3] in 1906, he began publishing paintings concerning social and political issues in magazines, which represented the beginning of Azerbaijani satirical graphic art.

Azimzade also actively participated in the Russian Revolution of 1905 and was the manager of the Department of Cultural Enlightenment of the People's Commissariat of Azerbaijan.

Azimzade worked closely with editor Jalil Mammadguluzadeh and published many illustrations and would become the chief artist of Molla Nasraddin.

[3] It is believed that he evaded political repressions due to his acquaintance with Mir Jafar Baghirov, who was the first secretary of the Azerbaijan Communist Party and an admirer of Azimzade's work.

During the beginning of World War II, Azimzade actively participated in the creation of the Agitokon posters written in both Azerbaijani and Russian with other Soviet artists.