Azorubine, also known as carmoisine, is an azo dye consisting of two naphthalene subunits.

It was delisted in 1963 because no party was interested in supporting the studies needed to establish safety.

[9] Azorubine has shown no evidence of mutagenic or carcinogenic properties and an acceptable daily intake (ADI) of 0–4 mg/kg was established in 1983 by the WHO.

[10]: 19  In rare instances, it may cause skin and respiratory allergic reactions even to FDA approved dosages.

[11]: 452  It is possible that certain food coloring may act as a trigger in those who are genetically predisposed, but the evidence is weak.