Pefloxacin is a quinolone antibiotic used to treat bacterial infections.

[1] Pefloxacin has been increasingly used as a veterinary medicine to treat microbial infections.

[4] Pefloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.

It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV,[5] which is an enzyme necessary to separate, replicated DNA, thereby inhibiting cell division.

Tendinitis and rupture, usually of the Achilles tendon, are class-effects of the fluoroquinolones, most frequently reported with pefloxacin.