Azuki-chan (Japanese: あずきちゃん) is a Japanese manga series about a young schoolgirl named Azusa Noyama, nicknamed Azuki-chan because when she was in first grade, Ken Takayanagi, a boy in her class, accidentally read her name, "Azusa(あずさ)", as "Azuki(あずき)".

Originally serialized in Nakayoshi magazine, it was later adapted into an anime by Madhouse.

Azuki lives with her mother, Keiko (けい子), with her father, Tadashi (正), and with her little brother, Daizu (大豆) in an apartment.

Azuki has three best friends, Kaoru Nishino (西野 薫 Nishino Kaoru), Midori Kodama (兒玉 持玉 翠 Kodama Jidama Midori) and Tomomi Takahashi (高橋 朋美 Takahashi Tomomi).

Kaoru secretly crushes on Ken but he doesn't accept her because he likes Azuki.

They seem to have a very close relationship except one episode when Jidama have gone out and sneaked in Azuki's bedroom because of an argument with her grandmother.

She doesn't have a crush on anyone but in an episode, she falls for a police officer who helped her when her house was robbed.

Makoto didn't notice her at first but at last he asks her to go on a date in his parents' hotel, and eventually gets closer with Tomo.

Before, in the first season, Azuki and Yūnosuke have their first kiss after he was beaten up by some middle school students.