The club competed in the Ukrainian Basketball SuperLeague (UBSL).

Established in 1992, Odesa played in the SuperLeague for most of its existence until it disappeared in 2016.

BC Odesa was one of the most distinguished basketball clubs in the country and has won the UBSL championship 4 times.

Following the death of its 1st president Arkadiy Tabachnyk in 1999, the club became municipal and, hence, changed its name to MBC Odesa.

In 2006, the club turned private again after its purchase by the current president Oleh Bychkov, and its name was changed to the present BC Odesa.