BETIC has its origins in a study conducted by Maharashtra University of Health Sciences, which concluded with a brainstorming meeting at Sahyadri Guest House, Mumbai in Dec 2009.

Its chairperson Dr. Anil Kakodkar invited IIT Bombay to develop a proposal for incubating a biomedical engineering and technology center based on hub-and-spoke model.

BETIC started functioning from OrthoCAD lab in IIT Bombay in early 2015, followed by two satellite centers established at Visvesvaraya National Institute of Technology, Nagpur and College of Engineering, Pune.

[4] Andhra Pradesh Med Tech Zone, Visakhapatnam and Gujarat Technological University, Ahmedabad also signed agreements with IIT Bombay for collaboration with BETIC.

At the 5th annual review, symposium and expo of BETIC held at IIT Bombay on 12–13 April 2019,[5] over 100 stakeholders representing the government, academia, medical community, startups, industry and investors discussed how to sustain, replicate and scale up the healthcare innovation eco-system.

They select problems from a curated list prepared in consultation with hospitals, evolve novel solution concepts, fabricate proof-of-concepts, and present them to a jury panel.