"Baby Sister" is a 1985 single by American singer La Toya Jackson, the first taken from her fourth album Imagination; which was released the following year.

The single was released in a 7" format in Japan and later in the United States.

Allmusic described the song as "too cute and overdone to be taken seriously" however The Baltimore Afro-American complimented the track as "new waveish" "ear candy".

[3][4] Jackson brought home a silver medallion and $1000 in prize money.

The song originally appeared on Janice Marie Johnson's 1984 solo album One Taste of Honey.