Nattō-derived Bacillus isolates include nootropics pyrazine and tetramethylpyrazine, as well as the anticoagulant enzyme nattokinase.
Bacillus subtilis is utilized in the production of hyaluronic acid and α-amylase.
Bacillus megaterium has been an important industrial organism for decades.
B. megaterium is also used for the production of pyruvate, vitamin B12, drugs with fungicidal and antiviral properties, etc.
[2] It produces enzymes for modifying corticosteroids, as well as several amino acid dehydrogenases.