Leipzig-Plagwitz (German: Bahnhof Leipzig-Plagwitz) is a railway station located in Leipzig, Germany.

The station opened on 20 October 1873.

The train services are operated by Deutsche Bahn and Erfurter Bahn.

Since December 2013 the station is served by the S-Bahn Mitteldeutschland.

As part of this, the platforms in Leipzig-Plagwitz had been moved directly north to Karl-Heine-Straße and received new entrances.