It followed the story of Lord Baltimore's hunt of the vampire Haigus as told by his three friends, Doctor Lemuel Rose, Thomas Childress Jr., and Demetrius Aischros.

The series is a part of Mignola and Golden's Outerverse, a shared universe with Joe Golem and other titles such as Lady Baltimore.

In an epilogue, the three companions relate their story to Simon Hodge, with Rose carrying Baltimore's tin heart in a box for evidence.

NB Chapel of Bones is an adaptation of the chapters Crescendo: Lux et Aeternum, Finale: Libera Me, and Coda from the novel Baltimore, or, The Steadfast Tin Soldier and the Vampire.

The series will be collected in a pair of hardcover omnibuses, the second of includes a new story, Monstrous, written by Mike Mignola and Christopher Golden, art by Ben Stenbeck, colors by Dave Stewart, and lettering by Clem Robins.