It was founded in 1872 as the Società Cooperativa di Credito Banca Popolare, and eventually expanded to 20 branches.
Between 1873 and 1881 the Society faced great difficulties due to a serious local economic depression; of the 600 and more factories engaged in the silk trade, fewer than 100 survived.
In 1912 two other local banks failed, but Banca Popolare survived and converted from a cooperative society to a corporation.
World War II again created a period of great difficulties, including the German occupation forces requisitioning of its headquarters from 1944 to 1945.
Banca Popolare di Novara (BPN) acquired a substantial stake in Banca Popolare di Lecco and seats on the board of directors.