Bandipur supports a wide range of timber trees including: teak (Tectona grandis), rosewood (Dalbergia latifolia), sandalwood (Santalum album V), Indian-laurel (Terminalia tomentosa), Indian kino tree (Pterocarpus marsupium), giant clumping bamboo (Dendrocalamus strictus), clumping bamboo (Bambusa arundinacea) and Grewia tiliaefolia.

There are also several notable flowering and fruiting trees and shrubs including: kadam tree (Adina cordifolia), Indian gooseberry (Emblica officinalis), crape-myrtle (Lagerstroemia lanceolata), axlewood (Anogeissus latifolia), black myrobalan (Terminalia chebula), Schleichera trijuga, Odina wodiar, flame of the forest (Butea monosperma), golden shower tree (Cassia fistula), satinwood (Chloroxylon swietenia), black cutch (Acacia catechu), Shorea talura (E), indigoberry (Randia uliginosa).

Bandipur National Park harbours the Asian elephant, gaur, Bengal tiger, sloth bear, four-horned antelope, golden jackal and dhole.

A list of medium to large-sized mammals in the park is given in the following census table published in 1997: Blue Peafowl are among the most commonly seen birds in Bandipur along with gray junglefowl, crows and drongos.

Bandipur is home to over 200 species of birds including crested honey buzzard, red-headed vulture, Indian vulture, Nilgiri flowerpecker, hoopoe, Indian roller, brown fish owl, crested serpent eagle, changeable hawk-eagle, osprey, as well as many bee-eater and kingfisher species are a common sight in winter.