She is the wife to notable Ugandan singer and politician Robert Kyagulanyi Ssentamu, alias Bobi Wine.
[3][4] She also co-owns and manages One love beach, a resort and recreational facility which was founded by her husband- Bobi Wine.
In 2013, she founded Caring Hearts Uganda, an NGO which focuses on adolescent girls, HIV/AIDS education and menstrual hygiene.
[7] In 2017, Barbie campaigned for her husband Bobi Wine to become a member of parliament and later for presidency in 2020 with her manifesto about women's rights.
Both were put under house arrest without a trial by Ugandan security forces in 2021 due to fears Bobi's public presence could incite riots.