Nyamitanga Division is located west and south of the central business district.
It borders with Kamukuzi Division and Kakoba Division in the north, Masha and Birere subcounties of Isingiro District in the south, and Nyakayojo Division in the west.
Nyamitanga Division has size of approximately 2,229 hectares The division consists of the neighborhoods of Katete, Karugangama, Kitobero, Nyamitanga hill, Nsiikye, and Ruti.
The Mbarara Catholic archdiocese and the Catholic radio, Radio Maria are located in Nyamitanga Division.
The 2014 census found Nyamitanga with the population of 23,314.