[2] Her family first lived in Albuquerque, New Mexico, for two years, and later she spent most of her childhood in Chicago, and then moved to New York City.
In 2013, she made her television debut, appearing in an episode of NBC comedy series 30 Rock.
In 2014, She made her Broadway debut in the comedic play You Can't Take It with You appearing opposite James Earl Jones and Rose Byrne.
[4] In 2017, Doss starred as Rita Hanson, a female lead, in the Broadway musical comedy Groundhog Day opposite Andy Karl.
In 2019, Doss also began appearing on a recurring basis on the sixteenth season of Grey's Anatomy.