[2] He is currently a professor in the Departments of Systems Biology, Biochemistry and Molecular Biophysics and Medicine and is a member of the Zuckerman Mind, Brain Behavior Institute.
Honig is particularly noted for innovating methods to compute and display the electrostatic potentials of macromolecules based on their 3D structures.
The computer programs DelPhi and GRASP were developed in his laboratory and are widely used by the academic and industrial communities.
[2]He has also made seminal contributions to the understanding of the spectroscopic and photochemical properties of visual pigments, to the computational prediction of protein structure and function, to the structural basis of protein-DNA interactions, and to the molecular principles that underlie cell-cell recognition.
His current research focus in on the genome-wide prediction of protein-protein interactions and their dysregulation in human disease.