The flowers are arranging in racemose or paniculate inflorescence, which have commonly opposite, very upright branches and pedicels.

The petals are oblong in shape and usually have denticulate margins and are abruptly narrowed to a rounded or obtuse, often mucronate tip.

[5] The native distribution of Bartonia virginica is eastern North America and is centered around the Atlantic coastal plain, with scattered inland populations.

[5] It has been found in Quebec and Nova Scotia of Canada to the US states of Wisconsin south to Florida and Louisiana.

It reaches the most western part of its range in eastern Minnesota, where it is very rare and listed as endangered, having been recorded in Goodhue and Anoka counties in white cedar swamps and peat bogs.