Barwise is a small, unincorporated community located on the level plains of the Llano Estacado about 10 mi (16 km) west of Floydada in western Floyd County, Texas.

The rail spur that passes through Barwise extended from the Fort Worth and Denver Railway junction at Estelline to Lubbock and Plainview.

As the story goes, Judge Barwise, who served as the Assistant General Attorney for the Fort Worth and Denver City Railway Company from 1902–1906 and later became a member of the board of directors, was the first person off the train to register at the local hotel.

Originally the town covered several city blocks and by the 1930s it had a hotel, a general store, a fertilizer dealer, a fueling station, a cotton gin, and two grain elevators.

[2] With improvements in state highways and the paving of many of the farm to market roads across West Texas, railroads became less important for shipping agricultural products and for general passenger travel.