Basilissa and Anastasia (died 68 AD) are early Christian martyrs of Rome, put to death during the reign of Nero.

[2] Basilissa and Anastasia were described as "Roman matrons of high rank and great wealth".

[1] The burials might have exposed Basilissa and Anastasia to more persecution, and they were arrested for collecting the relics of and burying the bodies of other martyred Christians.

They refused to recant their Christian faith and were beheaded with swords by order of Nero in 68 AD, after being tortured, including having their tongues torn out, their skins scraped with hooks, being burned with fire, and their breasts and feet cut off.

[1][2][3][4] Their relics are at Santa Maria della Pace Church in Rome.