Battle of Ghartiskari (Georgian: ღართისკარის ბრძოლა; Lezgian: Гьартискаридин Дяве) was fought either in October 1778 or 1779[clarification needed] in Ghartiskari between the personal guard of Ketevan Andronikashvili and a marauding Lezgin band.

After three attacks mounted by the Georgians with Ketevan's personal leadership, the Lezgins were defeated decisively.

Ketevan, a noblewoman on Heraclius II's court, was traveling from Mukhrani through Ghartiskari passage to the capital of the kingdom, Tbilisi accompanied by a royal guard detachment appointed by the king.

At the time, frequent North-Caucasian incursions posed great threat to travelers in Georgia.

After an ambush perpetrated by the Lezgins, Ketevan took charge of the guard and annihilated the marauders.