As a result of the battle, Macrinus was forced to seek peace, paying the Parthians a huge sum and abandoning the invasion of Mesopotamia that Caracalla had begun a year before.
During that period, several invasions of Parthian territory were led by Roman leaders, most notably the failed campaign of Crassus and the conquest of Mesopotamia by Trajan.
[...] This is no quarrel about boundaries or river beds; everything is at stake in this dispute in which we face a mighty king fighting for his children and kinsmen who, he believes, have been murdered in violation of solemn oaths.At first Macrinus, having no military experience and wishing to avoid a battle, tried to placate and reach an accommodation with Artabanus, offering to return all prisoners.
Artabanus rejected this, demanding financial compensation, the rebuilding of the destroyed towns and the cession of the Roman provinces of northern Mesopotamia, only recently conquered by Septimius Severus.
[7] On the first day of battle, the Romans deployed in a typical formation, with their infantry in the centre and their cavalry and light troops (Moorish javelin throwers) on the wings to protect their flanks.
[12] By this time, casualties on both sides were so great that "the entire plain was covered with the dead; bodies were piled up in huge mounds, and the dromedaries especially fell in heaps".
However, warfare between Rome and Persia soon resumed, as Ardashir and Macrinus' successor Alexander Severus fought over Mesopotamia, and hostilities continued intermittently until the Muslim conquests.