The battle resulted in the defeat of the Venetians, who could not be helped by Carmagnola's field army, with a loss of c. 2,500 men, 28 galleys, and 42 transport ships.

Francesco Sforza and Niccolò Piccinino, informed of what had happened, decided to board the ships at night together with the most chosen militias and to prevent Carmagnola from imitating them, they sent two spies to the Venetian camp with the task of spreading the word that Piccinino, in dawn, would have attacked them.

At the first light of dawn on 22 June, the Milanese fleet engaged the Venetian one which did not expect to be attacked again after the defeat of the previous evening.

To try to avoid defeat, Trevisan several times sent messengers to Carmagnola to come to his aid but these, fearing a surprise attack by Piccinino, decided not to intervene.

Many Venetian gelee, larger and with a greater draft than the Milanese ones, ran aground on the scree of the river and were easily captured, including the flagship of the Trevisan.