Benadryl challenge

[3] The challenge, which reportedly spread via the social media platform TikTok, instructs participants to film themselves consuming large doses of Benadryl and documenting the effect of tripping or hallucinating.

Numerous authorities have advised against the challenge, as deliberate overconsumption of diphenhydramine can lead to adverse effects, including confusion, delirium, psychosis, organ damage, hyperthermia, convulsions, coma, and death.

On September 24, 2020, the FDA formally released a statement advising parents and medical practitioners to be aware of the challenge's prevalence and its risks.

Several participants have been hospitalized as a result of the challenge, including three teenagers admitted to the Cook Children's Medical Center after consuming at least 14 diphenhydramine tablets,[6] and a 15-year-old Oklahoman teen who died from an overdose after attempting to take part.

Upon admission to an intensive care unit, it was found that he had suffered critical brain damage, and he died following six days of mechanical ventilation.

The recommended dosage of Benadryl tablets for adults is 1 to 2 tablets every 4 to 6 hours, ^{[

1

]} and only 1 tablet every 4 to 6 hours for children under the age of 12. ^{[

2

]}