Isolario contains an oval depiction of the world, a type of map invented by Bordone [3] and formalized into the equal-area elliptical Mollweide projection three centuries later.
Bordone's map shows a very distorted Mondo Novo (New World), displaying only the northern regions of South America.
North America, depicted as a large island, is labelled Terra del Laboratore ("Land of the worker"), almost certainly a reference to the slave trading in the area in those days and from which comes the name Labrador.
The book also contains a record of Francisco Pizarro's conquest of Peru, the earliest known printed account of this event.
One map displays a plan of "Temistitan" (Tenochtitlan, modern Mexico City) before its destruction by Cortez.