[1] The festival consists of lectures, exhibitions, interactive workshops, as well as meetings with scientists.

24 Nobel Prize laureates have participated to BergamoScienza since 2003, among them John F. Nash, Kari Mullis, Paul Crutzen, Roald Hoffman, Peter Agre, Aaron Ciechanover, Martin Chalfie, Eric Kandel, Barry Marshall, R. Timothy Hunt, Linda Buck, Bruce Beutler, James Dewey Watson.

Among innovative personalities, Jimmy Wales Wikipedia founder attended the conference.

[1] Notable past presenters include Burt Rutan (2004), Marvin Minsky (2006),[2] and Luciano Maiani (2008).

The 2009 festival included a presentation regarding Wikipedia,[3] as well as the exhibition "From the Moon to the Earth", organized by the Museo di Scienze Naturali Enrico Caffi.