(died 23 July 1579) was a Roman Catholic prelate who served as Bishop of Antequera, Oaxaca (1561–1579).

[1] Bernardo de Albuquerque was ordained a priest in the Order of Preachers.

[2] On 27 June 1561, he was selected by the King of Spain and confirmed by Pope Pius IV as Bishop of Antequera, Oaxaca.

[2] He served as Bishop of Antequera, Oaxaca until his death on 23 July 1579.

[1][2] In the year 1561, Bernardo de Albuquerque saw fit to destroy Mitla and exile most of its inhabitants, specifically the indigenous religious practitioners.