[2] Laney-Hamilton is the daughter of Yolanda Laney,[3] who played for Cheyney State and was also coached by C. Vivian Stringer.

On June 8, she was ruled out for the rest of the season after tearing her left anterior cruciate ligament (ACL).

[12] Laney-Hamilton had a breakout season in 2020 with the Atlanta Dream; she was named to the WNBA All-Defensive Team[13] and won the Most Improved Player Award.

[20] She led the Lynx to a second place regular season finish with a 16–8 win–loss record, and went on to score a game-high 23 points in the team's semi-final win over the first-seeded Townsville Fire.

[23] Stats current through end of 2024 season Laney is married to Jordan Hamilton, a fellow basketball player.

[26] In February 2024, Laney-Hamilton joined the WNBA Changemakers Collective and their collaboration with VOICEINSPORT (VIS) as a mentor, "aimed at keeping girls in sport and developing diverse leaders on the court and beyond the game.