In the year of 1482, Bianca was born in Lombardy, Italy,[1] from birth she was declared illegitimate and was the only daughter of Ludovico Sforza, (Regent of Milan[2]) and his lover at the time who was known as Bernardina de Corradis.

According to Antonio Zunico, it is clearly stated that her father, Ludovico promised Bianca to the illustrious powerful marquis and soldier, Galeazzo Sanseverino.

Although most of Ludovico's decisions were influenced by his desire to please his favourite, Galeazzo, he took a part for himself, he set this up so he could expand his own fuedal domains.

Recent historical-artistic studies and confirmed scientific hypotheses have shown that the landscape that is in the background to Leonardo da Vinci's Mona Lisa is taken from Bobbio.

[5] The landscape that forms the background to the picture is that of Bobbio seen from the Malaspina Dal Verme Castle, according to the scientific researcher Carla Glori.

[6] Furthermore, on the basis of these historical-artistic studies, she is identified as Bianca Giovanna Sforza, the girl portrayed in the painting by Leonardo da Vinci.