Henninger attended Archbishop Mitty High School in San Jose, California where she was an NSCAA All-American in 2006[4] and 2007.

During the second round of the NCAA tournament in a match against Oklahoma State, she saved two penalty kicks and scored one in a 6–5 shootout victory.

[11] On 7 February 2013, Henninger was drafted by FC Kansas City for the inaugural season of the National Women's Soccer League.

[12] On 13 January 2014, Henninger was traded to the Houston Dash in exchange for the first pick of the third round (19th overall) in the 2014 NWSL College Draft.

[16][17] Born in the United States, Henninger was a member of the 2010 FIFA U-20 Women's World Cup U.S. squad that was eliminated in the quarterfinals.

[18] She also played in all 5 games for the gold medal-winning U.S. team in the 2010 Concacaf U20 World Cup qualifying tournament in Guatemala, during which she surrendered 2 goals.

[22] Henninger has 4 caps with the national team, sharing goalkeeping duties with teammate Cecilia Santiago.