[8][9] In 1997, days after graduating from Emerson College, de la Garza was working full-time on-air at WTEN, the ABC affiliate in Albany, New York.
De la Garza covered politics during Governor George Pataki's administration including Senate Majority leader Joe Bruno and former Speaker of the State Assembly Sheldon Silver, interviewing then-candidates Hillary Clinton and Chuck Schumer.
[citation needed] In 1999 de la Garza joined KGTV the ABC affiliate in San Diego as a reporter and fill-in anchor.
[citation needed] She received an award from the San Diego press club for her investigative reports on an illegal factory she uncovered for smuggling undocumented workers across the US border and locking them up overnight at their facility.
[13][failed verification] In 2001 de la Garza returned east, joining Boston Fox affiliate WFXT as a reporter and lead weekend anchor.
[16][17] Her exclusive interview with a survivor of the Craigslist killer Philip Markoff was picked up nationally on ABC's Good Morning America and Inside Edition.
There she scored a world exclusive interview with Mohamed Al-Fayed in London, who gave candid remarks about his beliefs that the Royal Family was involved in the death of Princess Diana and his son Dodi.
[19][failed verification] De la Garza covered several Super Bowls and World Series playoffs over a span of several years in Boston.
[21] She had a cameo on the hit NBC TV show American Odyssey and a co-hosting guest spot on Hollywood Today Live with Ross Mathews.
[citation needed] In 2019 de la Garza created a talk show on the careers of those in the beauty and personal care industry, where celebrity stylists, manicurists and estheticians revealed how they worked with their A list clientele.
[29] In 2021, de la Garza appeared as a guest host on Newsmax, and in January 2022, she announced she would co-anchor the midday show John Bachman Now.