James Jackson "Biff" Henderson, Jr. (born October 3, 1946) is an American comedian and television personality best known for his work on the Late Show with David Letterman.

He was the show's stage manager and appeared in occasional humorous segments, which often involved interviewing people at public places and events.

Henderson graduated from Hillside High School in Durham, and earned a degree in business administration from Hampton Institute.

His need for a restroom in the RCA Building led to a chance encounter with a janitor who introduced him to an NBC sales executive.

[2] Henderson frequently participated in the on-screen antics and sometimes was the star of short segments recounting his humorous adventures in New York.