The call is interrupted by horrific sounds suggesting an animal attack, and the pair set out to help, only to fall prey themselves.
Seven years later, Charlie's nephew, Derek, lives with his mother Gwen and his emotionally abusive stepfather, Mitch.
Derek prepares to take advantage of Mitch's planned work trip to use his cabin for a weekend party with classmates he hopes to impress.
Mitch picks Derek up from the police station and tells him his actions make him responsible for the massacre.
Sam and Derek suspect that Mitch is the werewolf and attempt to piece together proof, as tensions rise in the household.
Charlie cautions the teens that an accusation cannot be made without DNA evidence to compare to a hair sample he kept from the werewolf.
Derek arrives to find another group of youths eager to explore the site, which is now locally notorious as the scene of a massacre.