He played alongside Muddy Waters, Howlin' Wolf, Jimmy Reed, and Albert King.
"[6] He focused on his music career because it was more lucrative, forming his own band Big George & the Houserockers.
[4] Blues guitarist Albert King played in Brock's band before forming his own.
[6] In 1952, Brock opened his own nightclub, Club Caravan, near North Garrison and Franklin avenues.
Brock worked as a bouncer and performed there with his band which at times featured King, Big Baddy Smitty, or Riley Coatie on lead guitar.
[4] The club hosted acts such as Howlin' Wolf, Muddy Waters, Ike & Tina Turner, and Jimmy Reed.
He opened another Club Caravan at Delmar Boulevard and Taylor Avenue, but that closed in the late 1980s.
[6] In 2005, Brock signed to the label Cat Head Delta Blues & Folk Art.